7th Cancer Cachexia Conference
September 28-30, 2023  |  Edinburgh, Scotland

Advancing knowledge and clinical interventions in cancer cachexia

 

Program update: March 6, 2023

Preliminary Program Outline - In Person

CCS will again be using the Whova mobile application (URL to come). Presentations will be recorded but due to prohibitive cost, there will be no virtual attendance or live streaming.


Thursday, September 28, 2023

8:00 am

Welcome and Introductory Remarks

CCS President

Teresa Zimmers, PhD, Oregon Health & Science University, USA

Clinical Advances in Cancer Cachexia

Session A: State-of-the-Knowledge: Clinical Fundamentals of Cancer Cachexia

Co-Chairs: TBN

8:10 am

Objective metrics for cancer cachexia assessments

TBN

8:40 am

Cancer cachexia clinical trial endpoints

Barry Laird, MBChB MRCGP MD - University of Edinburgh, Scotland, UK

9:10 am

Update on consensus definition of cancer cachexia

Vickie Baracos, PhD - University of Alberta, CANADA

9:40 am

Cardiac wasting in advanced cancer & its therapeutic implications

Stefan Anker, PhD & MD - Charité Berlin, GERMANY

10:10 am

Break

Session B: Recent Clinical Trials and Trial Results

Co-Chairs: TBN

10:30 am

Trial design, efficacy, safety, and tolerability of ponsegromab in cancer cachexia

John D. Groarke, MBBCh MSc MPH – Pfizer, Inc.

11:00 am

Central relays in cancer cachexia

Daniel Marks, MD & PhD – Oregon Health & Science University, USA

11:30 am

Talk selected from abstract submissions

12:00 pm

Short talk – Developing a Cachexia Lexicon

Elif Andac-Jones, PhD - Cancer Support Community, USA

12:15 pm

Short talk selected from abstract submissions

12:30 pm

Lunch Break

Considering People with Cancer Cachexia

1:30 pm

Patient-Provider-Caregiver Panel

Chair: Martin Kochanczyk, PhD – Cancer Cachexia Society, USA

 

History of Cancer Cachexia Research in Scotland

Chair: TBN

3:00 pm

History of cancer cachexia research in Glasgow

Donald McMillan, PhD – University of Glasgow, Scotland, UK

3:25 pm

History of cancer cachexia research in Edinburgh

Steve Wigmore, MBBS, MD – University of Edinburgh, Scotland, UK

3:45 pm

Break

 

Next Gen Researchers in Cancer Cachexia

Co-Chairs: Andrea Bonetto, PhD – University of Colorado, USA and Maria Rohm, PhD - Helmholtz Center Münich, GERMANY

 

4:00 pm

NextGen Talk 1 from submissions

4:15 pm

NextGen Talk 2 from submissions

4:30 pm

NextGen Talk 3 from submissions

4:45 pm

NextGen Talk 4 from submissions

5:00 pm

NextGen Talk 5 from submissions

5:15 pm

NextGen Talk 6 from submissions

5:30 pm

*Social Events

 

Whisky tasting

Ghost tour of Edinburgh

Walking tour of Edinburgh

 

Friday, September 29, 2023

7:00 am

Mentoring Event

NCI/CRUK Cancer Grand Challenge - CANCAN

Chair: Bette Caan, DrPH - Kaiser Permanente, USA

8:30 am

CANCAN talk 1

Sheng Tony Hui, PhD – Harvard University, USA

9:00 am

CANCAN talk 2

Janelle Ayres, PhD – Salk Institute for Biological Studies, USA

 9:30 am

CANCAN talk 3

David Lewis, PhD - Beatson Institute, Scotland, UK

9:45 am

Working Towards a Precision Medicine Framework in Cancer Cachexia: Learning from Patients

Richard Dunne, MD - University of Rochester, USA

10:30 am

Break

Tumor as driver of cachexia

Co-Chairs: TBN

11:00 am

Talk title to be confirmed

Min Li, PhD – The University of Oklahoma Health Sciences Center

11:30 am

Heterogeneity of lung cancer and cachexia in mouse models

Rodney Infante, MD PhD - University of Texas Southwestern Medical Center, USA

12:00 pm

Racial/Ethnic heterogeneity

Jose Trevino, MD - Virginia Commonwealth University, USA

12:30 pm

Short talk selected from abstracts

12:45 pm

Lunch break

1:30 pm

Poster Viewing

Cachexia/Muscle wasting as a driver of cancer

Co-Chairs: TBN

4:00 pm

Muscle growth slows tumor growth

Bert Blaauw, PhD - Veneto Institute of Molecular Medicine, ITALY

4:30 pm

Host Murf1 deletion preserves muscle and slows pancreatic cancer progression

Andrew Judge, PhD - University of Florida, USA

5:00 pm

Effects of Murf1 host deletion on tumor microenvironment

Jason Doles, PhD - Indiana University, USA

5:15 pm

Short talk selected from abstracts

5:30 pm

Short talk selected from abstracts

7:00 pm

*Dinner

9:00 pm

*Cèilidh – a traditional Scottish party

 

Saturday, September 30, 2023

7:00

Social Event

Multi-organ crosstalk in Cancer Cachexia

Co-Chairs: TBN

8:30 am

Gut microbiome alterations and metabolic disorders in acute myeloid leukemia

Laure Bindels, PhD - Université catholique de Louvain, BELGIUM

9:00 am

Tumor - host interactions revealed in drosophila models of cachexia

Tor Erik Rusten, PhD – University of Oslo, NORWAY

9:30 am

Short talk selected from abstract submissions

9:45 am

Short talk selected from abstract submissions

10:00 am

Break

Keynote Address

10:15 am

Introduction of Kenneth Fearon Lecture Speaker

Marie Fallon, MD - University of Edinburgh, Scotland, UK

10:20 am

Kenneth C.H. Fearon Keynote Lectureship

Denis Guttridge, PhD - Medical University of South Carolina, USA

Cutting Edge Research in Cancer Cachexia

Co-Chairs: TBN

11:30 am

Cutting Edge Talk 1 from abstracts

11:35 am

Cutting Edge Talk 2 from abstracts

11:40 am

Cutting Edge Talk 3 from abstracts

11:45 am

Cutting Edge Talk 4 from abstracts

11:50 am

Cutting Edge Talk 5 from abstracts

11:55 pm

Cutting Edge Talk 6 from abstracts

12:00 pm

Lunch Break

Immunometabolism of Cancer Cachexia

Co-Chairs: TBN

1:30 pm

Immune checkpoint inhibition and cancer cachexia

Chris Coss, PhD - The Ohio State University, USA

2:00 pm

HMGB1 in cancer cachexia

Marco Bianchi, MD - San Raffaele University, ITALY

2:30 pm

Short talk: Hepatic metabolism, IL-6, cancer cachexia

Aaron Grossberg, MD PhD - Oregon Health & Science University, USA

2:45 pm

Short talk selected from abstract submissions

3:00 pm

Break

Novel targetable pathways, novel therapeutic strategies

Co-Chairs: TBN

3:30 pm

A novel target for tumor growth and muscle wasting

Marco Sandri, PhD - University of Padova, ITALY

4:00 pm

Long noncoding RNAs in the regeneration of aging muscle

Miriam Gorospe, PhD – National Institute on Aging, National Institutes of Health, USA

4:30 pm

COVID, Cachexia and Cancer

David Glass, MD, PhD – Regeneron, USA

5:00 pm

GDF15 in cancer cachexia and beyond

Bei Zhang, PhD - Pfizer, USA

5:30 PM

Short talk selected from abstract submissions

5:45 PM

Presentation of awards

6:00 PM

Closing Remarks

 

Teresa Zimmers, PhD Oregon Health & Science University, USA and Andrew Judge, PhD University of Florida, USA

 

*Certain social events, including the whiskey tasting, dinner and Cèilidh require additional fees.