7th Cancer Cachexia Conference
September 28-30, 2023  |  Edinburgh, Scotland

Advancing knowledge and clinical interventions in cancer cachexia

 

Program update: May 31, 2023

Preliminary Program Outline - In Person

CCS will again be using the Whova mobile application (URL to come).
Presentations will be recorded but due to prohibitive cost, there will be no virtual attendance or live streaming.


Education Committee Initiatives

Please view the video for information on these Conference initiatives.
See you in Edinburgh!

 


Thursday, September 28, 2023

8:00 am

Welcome and Introductory Remarks
CCS President
Teresa Zimmers, PhD, Oregon Health & Science University, USA


Clinical Advances in Cancer Cachexia

Session A: State-of-the-Knowledge: Clinical Fundamentals of Cancer Cachexia

Co-Chairs: TBN

8:10 am

Objective metrics for cancer cachexia assessments
TBN

8:40 am

Endpoints in cachexic clinical trials - taking stock, moving forward

Barry Laird, MBChB MRCGP MD - University of Edinburgh, Scotland, UK

9:10 am

Update on consensus definition of cancer cachexia
Vickie Baracos, PhD - University of Alberta, CANADA

9:40 am

Cardiac wasting in advanced cancer & its therapeutic implications
Stefan Anker, PhD MD - Charité Berlin, GERMANY

10:10 am

Break

Session B: Recent Clinical Trials and Trial Results

Co-Chairs: TBN

10:30 am

Ponsegromab as a potential therapy for cancer cachexia
John D. Groarke, MBBCh MSc MPH – Pfizer, Inc.

11:00 am

Central relays in cancer cachexia
Daniel Marks, MD PhD – Oregon Health & Science University, USA

11:30 am

Talk selected from abstract submissions

12:00 pm

Developing a Cachexia Lexicon
Elif Andac-Jones, PhD - Cancer Support Community, USA

12:15 pm

Short talk selected from abstract submissions

12:30 pm

Lunch Break


Considering People with Cancer Cachexia

1:30 pm

Patient-Provider-Caregiver Panel

Chair: Martin Kochanczyk, PhD – Cancer Cachexia Society, USA


History of Cancer Cachexia Research in Scotland

Chair: TBN

3:00 pm

History of cancer cachexia research in Glasgow
Donald McMillan, PhD – University of Glasgow, Scotland, UK

3:25 pm

Cachexia research- the Edinburgh perspective

Stephen Wigmore, Regius Chair of Clinical Surgery – University of Edinburgh, Scotland, UK

3:45 pm

Break


Next Gen Researchers in Cancer Cachexia

Co-Chairs:
Andrea Bonetto, PhD – University of Colorado, USA and
Maria Rohm, PhD - Helmholtz Center Münich, GERMANY
4:00 pm  NextGen Talk 1 from submissions
4:15 pm  NextGen Talk 2 from submissions
4:30 pm  NextGen Talk 3 from submissions
4:45 pm  NextGen Talk 4 from submissions
5:00 pm  NextGen Talk 5 from submissions
5:15 pm  NextGen Talk 6 from submissions
5:30 pm *Social Events

• Whisky tasting
• Ghost tour of Edinburgh
• Walking tour of Edinburgh

 

Friday, September 29, 2023

7:00 am

Mentoring Event


NCI/CRUK Cancer Grand Challenge - CANCAN

Chair: Bette Caan, DrPH - Kaiser Permanente, USA

8:30 am

The role of IL-6 in the C26 cancer cachexia model
Tony Hui, PhD – Harvard University, USA

9:00 am

CANCAN talk 2
Janelle Ayres, PhD – Salk Institute for Biological Studies, USA

9:30 am

The Role of Positron Emission Tomography in Understanding Cancer Cachexia

David Lewis, PhD - Cancer Research Beatson Institute, Scotland, UK

9:45 am

Working Towards a Precision Medicine Framework in Cancer Cachexia: Learning from Patients
Richard Dunne, MD - University of Rochester, USA

10:30 am

Break


Tumor as driver of cachexia

Co-Chairs: TBN

11:00 am

Pancreatic Cancer Cachexia

Min Li, PhD – The University of Oklahoma Health Sciences Center

11:30 am

Modulating Key Metabolic Pathways - Impact on Cachexia and Malnutrition

Bei Zhang, PhD - Pfizer, USA

12:00 pm

Racial/ethnic heterogeneity in cancer cachexia

Jose Trevino, MD - Virginia Commonwealth University, USA

12:30 pm

Short talk selected from abstracts

12:45 pm

Lunch break

Artelo Biosciences Symposium

1:30 pm

Poster Viewing


Cachexia/Muscle wasting as a driver of cancer

Co-Chairs: TBN

4:00 pm

Muscle-tumor crosstalk during cancer cachexia

Bert Blaauw, PhD - Veneto Institute of Molecular Medicine, ITALY

4:30 pm

Host Murf1 deletion preserves muscle and slows pancreatic cancer progression
Andrew Judge, PhD - University of Florida, USA

5:00 pm

Tumor-host cross talk: delineating the reciprocal contribution of muscle wasting to tumor progression

Jason Doles, PhD - Indiana University, USA

5:15 pm

Short talk selected from abstracts

5:30 pm

Short talk selected from abstracts

7:00 pm

*Dinner

9:00 pm

*Cèilidh – a traditional Scottish party

 

Saturday, September 30, 2023

7:00 am

Cachexia Speed Networking


Multi-organ crosstalk in Cancer Cachexia

Co-Chairs: TBN

8:30 am

Gut microbiome alterations and metabolic disorders in acute myeloid leukemia
Laure Bindels, PhD - Université catholique de Louvain, BELGIUM

9:00 am

Tumor - host interactions revealed in drosophila models of cachexia
Tor Erik Rusten, PhD – University of Oslo, NORWAY

9:30 am

Short talk selected from abstract submissions

9:45 am

Short talk selected from abstract submissions

10:00 am

Break


Keynote Address

10:15 am

Introduction of Kenneth Fearon Lecture Speaker
Marie Fallon, MD - University of Edinburgh, Scotland, UK

10:20 am

How Different Environments Can Influence Our Understanding of Muscle Wasting in Cancer Cachexia
Denis Guttridge, PhD - Medical University of South Carolina, USA


Cutting Edge Research in Cancer Cachexia

Co-Chairs: TBN

11:30 am

Cutting Edge Talk 1 from abstracts

11:35 am

Cutting Edge Talk 2 from abstracts

11:40 am

Cutting Edge Talk 3 from abstracts

11:45 am

Cutting Edge Talk 4 from abstracts

11:50 am

Cutting Edge Talk 5 from abstracts

11:55 pm

Cutting Edge Talk 6 from abstracts

12:00 pm

Lunch Break


Immunometabolism of Cancer Cachexia

Co-Chairs: TBN

1:30 pm

Relationships Between Cancer Cachexia, Elevated Drug Clearance, and Immune Checkpoint Inhibitor Response

Chris Coss, PhD - The Ohio State University, USA

2:00 pm

HMGB1 in cancer cachexia
Marco Bianchi, MD - San Raffaele University, ITALY

2:30 pm

IL-6 and adaptive metabolism in cancer cachexia
Aaron Grossberg, MD PhD - Oregon Health & Science University, USA

2:45 pm

Short talk selected from abstract submissions

3:00 pm

Break


Novel targetable pathways, novel therapeutic strategies

Co-Chairs: TBN

3:30 pm

A novel target for tumor growth and muscle wasting
Marco Sandri, PhD - University of Padova, ITALY

4:00 pm

Long noncoding RNAs in the regeneration of aging muscle
Miriam Gorospe, PhD – National Institute on Aging, National Institutes of Health, USA

4:30 pm

Age-related effects creating a permissive environment for sarcopenia

David Glass, MD, PhD – Regeneron Pharmaceuticals Inc., USA

5:00 pm

Heterogeneity of cachexia development in NSCLC

Rodney Infante, MD PhD - University of Texas Southwestern Medical Center, USA

5:30 pm

Short talk selected from abstract submissions

5:45 pm

Presentation of awards

6:00 pm

Closing Remarks
Teresa Zimmers, PhD – Oregon Health & Science University, USA and Andrew Judge, PhD – University of Florida, USA

 

*Certain social events, including the whiskey tasting, dinner and Cèilidh require additional fees.